Early Predictors of Pre-eclampisa

Pre-eclampsia is defined by the International Society for the Study of Hypertension in Pregnancy as, “Gestational hypertension of at least 140/90 mm Hg on two separate occasions 4-6 h apart accompanied by significant proteinuria of at least 300 mg in a 24 h collection of urine. It arises de novo after the 20th week of gestation in a previously normotensive woman and resolves completely by the 12th postpartum week.” Pre-eclampsia is a major reason for maternal and perinatal mortality and morbidity worldwide inflicting 15% of all direct maternal deaths and a multiple increase in perinatal mortality with induced prematurity being the most perpetrators.